IL-7 regulates glucose uptake in naive and activated T cells. (A,B) T cells were analyzed immediately after purification (F) or after culture overnight without stimulation (N) or in IL-7 for (A) glucose uptake and (B) Glut1 protein levels. (C,D) T cells were analyzed freshly isolated (F) and after stimulation with anti-CD3 and anti-CD28 (S), then neglect (N), IL-7, or IL-2 for (C) glucose uptake and (D) Glut1 protein levels. Values represent means plus or minus the standard error of the mean (SEM) of triplicate samples. By Student t test, *P < .03, **P < .001.