Inhibition of ex vivo collagen-induced aggregation of rat platelets after injection of AAPP. SD rats were administered rAAPP (0.1, 0.3, or 1.0 mg/kg) intravenously, and blood was drawn 10 minutes after the administration. Treatment with rAAPP results in inhibition of platelet aggregation in response to collagen, compared with treatment with PBS and rTrx, but has no effect on the ADP response. Results are means plus or minus SEM for 3 animals in each group.