αB-crystallin is expressed in a subset of tumor vessels. (A) Immunofluorescence analysis of αB-crystallin expression (red) and endothelial cells (visualized by UEA-1 binding [green]) in normal human kidney. (B) Expression of αB-crystallin in endothelial cells (indicated by arrows) in human renal cancer. Arrowheads indicate vessels lacking αB-crystallin expression. (C) Magnification of tumor vessel in human renal cancer showing expression of αB-crystallin in endothelial cells. (D) Expression of αB-crystallin in smooth muscle cells and endothelial cells (arrows) in human renal cancer. (E) Normal human lung vessels lacking expression of αB-crystallin in endothelial cells. (F) αB-crystallin expression in endothelial cells in human lung cancer. Bars equal 100 μm.