AV513 has different potency in AAV-FVIII and severe hemophilia A dog whole blood TEG assays. TEG R times were determined in citrated whole blood from dogs with low Factor VIII (AAV-FVIII) or severe, treatment-naive hemophilia A in the presence or absence of added AV513. TEG R times for each dose were averaged from 3 dogs/group, with error bars representing SD.