CD4⁺ T_EMs mediate GVL against mBC-CML. Lethally irradiated B6 mice were reconstituted with T cell–depleted B6^bm12 BM, 10⁴ B6 mBC-CML cells, with no T cells, or with 10⁶ CD4⁺ T_EMs or 5 × 10⁵ CD4⁺ T_Ns. Shown are results combined from 2 similar independent experiments. P = .024 comparing BM alone versus T_EM recipients.