Effect of Wogonin on tumor growth in vivo. (A) Eleven H-2qRag−/−γc−/− mice were xenografted with 5 × 107 CEM and 3 days after grafting 6 mice were randomly chosen for Wogonin treatment (200 mg/kg) at each second day until day 13 as indicated. Tumor size was measured 11 days after grafting. Results are representative of 3 independent experiments. (B) Examples of an untreated and a Wogonin-treated mouse at day 15.