Flowchart of individuals included in the analysis. Between 1995 and 2018, 170 individual patients were treated for a confirmed diagnosis of TTP. Of these, 14 died during the index TTP episode, and another 19 had less than 1 month of follow-up after recovery from TTP. The remaining 137 patients were included in the analyses of stroke after TTP. A subset of 52 patients had available measurements of ADAMTS13 activity in remission, and could be evaluated for association of remission ADAMTS13 with subsequent stroke. *One of the 52 patients had had a stroke before the first measurement of remission ADAMTS13 and was excluded from this analysis.