Effects of α2AP supplementation/inhibition. (A) Representative images of IVC thrombus formation in α2AP^−/− mice after 5 hours’ ligation after administration of α2AP or α2AP + α2AP-inactivating antibody (α2AP-I) as labeled. (B) Vein thrombus weight in these groups in milligram/gram of body weight as labeled. Each symbol represents a single experiment, N = 14. The horizontal red and blue lines in the graph show, for reference, the mean thrombus weight in α2AP^+/+ and α2AP^−/− mice, respectively. ****P < .0001; one-way ANOVA (among 4 groups).