Comparison of apheresis samples in postinduction and relapsed/refractory cohorts. Percent of T cells with the CD8⁺ CD45RO⁻ CD27⁺ memory phenotype (A), CD4/CD8 ratio (B), and PD9 of ex vivo stimulation (C) with agonistic anti-CD3/anti-CD28–conjugated microbeads. Rightmost 2 columns in each graph depict each parameter in the relapsed/refractory cohort, separated according to response to CART-BCMA. In each analysis, the postinduction cohort was compared with the overall relapsed/refractory cohort and to the subset of the relapsed/refractory cohort that achieved at least partial response (PR) to CART-BCMA.