Studies comparing T-cell depletion with conventional GVHD prophylaxis
ABL indicates ablative; T10B9, monoclonal antibody directed against CD3; Elutr, counterflow elutriation, a technique for separating cell populations based on centrifugation; CNI, calcineurin inhibitor; NS, nonsignificant; NRM, nonrelapse mortality; PFS, progression-free survival; OS, overall survival; HR, hazard ratio; UNR, unrelated; BM, bone marrow; PBSC, peripheral blood stem cell; and MUD, matched unrelated donor.
*The number of AML patients is unclear from this publication. Two doses of thymoglobulin were tested and the higher dose had a more beneficial effect on GVHD.