*GRADE system: Grade 1B, a strong recommendation that can be applied uniformly in most patients given that there is confidence that the benefits of testing do not outweigh the harm, burden, and costs based on moderate-quality evidence .51
†Canadian Task Force on Preventative Health Care system: II-2B, fair evidence to recommend the clinical preventative action; evidence from well-designed cohort or case-control studies.26
‡GRADE system: Grade 1B, a strong recommendation that can be applied to most patients in most circumstances, based on moderate quality data; Grade 2C, a weak recommendation and other alternatives may be equally reasonable, based on low- or very-low-quality evidence.47
§RCOG: Grade C, a recommendation derived from a body of evidence consisting of well conducted case-control or cohort studies directly applicable to the target population and demonstrating overall consistency of results or extrapolated evidence from high-quality systematic reviews of case-control or cohort studies or from high-quality case-control or cohort studies.49