Figure 2.
Distribution of Ph-like ALL subgroups among children, adolescents, and young adults. CRLF2 rearrangements are the most prevalent genetic alteration across all age groups. ABL-class gene rearrangements are more frequent in childhood, whereas there is a striking increase in the frequency of JAK2 rearrangements among young adults with Ph-like ALL. HR, high-risk. Adapted from Roberts et al,6 with permission.