Aggressive lymphomas with MYC translocations. (A) MYC-rearranged DLBCL. Note large blastic cells with broad cytoplasm and large nuclei, finely dispersed nuclear chromatin, and single prominent nucleoli (H&E stain; magnification, 400×). (B) BCLU. In comparison with BL, the tumor cells are slightly larger and harbor more irregular nuclei, sometimes with single nucleoli. Some histiocytes are interspersed, but there is no clearcut starry sky pattern (H&E stain; magnification, 400×). (C) PBL MYC rearranged. The cells are small to intermediate in size. Giemsa stain highlights the plasmablastic features of the tumor cells. CD20 was negative in this tumor (magnification, 1000×).