Frequent cytogenetics defining intermediate-risk AML
The categorization of the cytogenetic findings in the table is based on the classification systems published by SWOG/ECOG,3 CALGB,4 and MRC.2,5
*No chromosome aberrations after analysis of 20 or more BM metaphases.
†According to the SWOG/ECOG classification included within the group “abn 11q” and categorized as unfavorable risk.3
‡Unfavorable risk according to the SWOG/ECOG classification3 and according to the revised version of the MRC classification5 based on multivariable analyses.
§Within the SWOG/ECOG classification, “abn 20q” is classified as unfavorable.3
‖Within the CALGB classification classified as adverse risk in terms of overall survival.4