Figure 4.
Simplified representation of signaling pathways associated with CRLF2 rearrangements and JAK mutations in which TSLP induces phosphorylation of STAT5, PI3K, and ERK. Potential therapeutic inhibitors and their targets are indicated.
Simplified representation of signaling pathways associated with CRLF2 rearrangements and JAK mutations in which TSLP induces phosphorylation of STAT5, PI3K, and ERK. Potential therapeutic inhibitors and their targets are indicated.
