Diagnostic criteria for preeclampsia with PE/HELLP syndrome, TTP, and C-TMA
Diagnostic criteria for preeclampsia, preeclampsia with severe features/HELLP syndrome, and eclampsia are adapted and simplified from the American College of Obstetricians and Gynecologists.13,14 Diagnostic criteria for TTP are from the randomized controlled trial documenting efficacy of plasma exchange.16 Diagnostic criteria for C-TMA are from the clinical trials that supported approval of eculizumab (described in these studies as atypical hemolytic–uremic syndrome).21