Table 4.
Published studies of nonspecific agents for reversal of oral factor Xa inhibitor anticoagulant effect in animals and humans
APTT indicates activated partial thromboplastin time; aPCC, activated prothrombin complex concentrate; ETP, endogenous thrombin potential; INR, international normalized ratio; LT, lag time; PCC, prothrombin complex concentrate; 3-PCC, 3-factor PCC; 4-PCC, 4-factor PCC; PT, prothrombin time; rVIIa, recombinant activated factor VII; TG, thrombin generation; TP, thrombin potential; and TTP, time to peak.
Adapted from Siegal23 with permission.
