Prognostication of FDG-PET/CT in early-stage HL. Shown is the PFS according to the result of interim FDG-PET/CT (status-post 2-3 ABVD cycles) of 57 early-stage (A) and 28 advanced-stage (B) HL patients. Treatment was continued regardless of FDG-PET/CT result. (Reprinted with permission from Hutchings et al.³⁹ ) (C) PFS for 88 patients with early-stage nonbulky HL treated on a US Cooperative group phase 2 study using AVG frontline therapy. Incl indicates including; MRU, minimal residual uptake. (Reprinted with permission from Straus et al.³⁸ )