Figure 1.
“Word cloud” of mutations recurrently associated with MDS. Many of these mutations are commonly included on currently available molecular genetic testing assays (“mutation panels”) designed to aid in diagnosis and prognosis of patients with myeloid neoplasms. Gene font size is proportionate to the square root of mutation frequency, to allow readability of infrequent recurrent mutations, and color corresponds with putative or known biological function of encoded proteins. Data on mutation frequency from Haferlach.10 Figure cocreated with Rafael Bejar, University of California–San Diego.