Examples of clinical scenarios in FN for which evidence-based recommendations are not available
All patients were seen by the author at the NIH Clinical Center. Patient 1 was downgraded to ceftriaxone; patient 2 was treated with piperacillin-tazobactam and defervesced uneventfully; patient 3 was started on voriconazole, but the bronchoalveolar lavage showed Cunninghamella and he was successfully treated for mucormycosis with liposomal amphotericin B and surgical resection; patient 4 had Enterococcus faecalis bacteremia; patient 5 had CMV pneumonitis.
AML indicates acute myelogenous leukemia; VRE, vancomycin-resistant enterococcus; ANC, absolute neutrophil count; and ALL, acute lymphocytic leukemia.