Fig. 3.
Thalidomide reduced myeloma tumor burden only in SCID-hu hosts implanted with human liver.
Sections (stained with hematoxylin and eosin) of decalcified human bones of CMC control (A,C) and thalidomide-treated (B,D) hosts inoculated with myeloma cells from patient 9. Note marked decrease in myeloma infiltration in the section from a host implanted with human liver (SCID-hu B+L, [D]) and no change in the section from SCID-hu B (B) compared with their respective CMC-treated (SCID-hu B+L, [C] and SCID-hu B, [A]) controls.