Genes expressed at least 5-fold lower in CD34⁺ marrow cells from patients with low-risk MDS than in healthy controls.

The 161 genes that were more than 5-fold down-regulated in CD34⁺ marrow cells from patients with low-risk MDS compared with the CD34⁺ cells from healthy controls includeIEX1 (radiation-inducible immediate-early response gene),RAI3 (retinoic acid–induced gene), H4M (H4 histone family), p63 (tumor protein 63), and TM4SF(transmembrane 4 superfamily). Expression of these genes is displayed by GeneSpring software for each of the samples. Each single dot represents the normalized expression level of one gene. “No.” indicates sample number.