Fig. 2.
TRAF gene family expression in normal and neoplastic B cells.
Expression of TRAF1-6, I-TRAF, and TRIP mRNA in B lymphocytes from patients with B-CLL (lanes 1-5), healthy blood donors (lanes 6-10), a tonsil specimen (lane 11), the human B-cell precursor lines MHH-CALL 2 (lane 12) and MHH-CALL4 (lane 13), the human T-cell leukemia line MOLT4 (lane 14), the CD5+, EBV+ B-cell line EHEB (lane 15), and the EBV-Burkitt cell line BJAB (lane 16). A hAPO-5b RNAse protection assay was used for all experiments. A quantity of 10 μg total RNA was used per lane.