Fig. 5.
Erythrocyte adhesion to fibrin at low shear rate.
As washed erythrocytes were perfused over fibrin polymerized from PFP at a wall shear rate of 50 s−1, firm adhesion to fibrin was observed (A). When erythrocytes were perfused over purified fibrin, no firm adhesion and transient pausing to fibrin were observed (B). When this fibrin surface was coated with TSP (25 μg/mL) prior to erythrocyte perfusion, adhesion was observed (C). This adhesion was attenuated in the presence of soluble fibrinogen (D). Flow was from right to left.