Fig. 6.
Erythrocyte adhesion under pathophysiologic conditions.
As PFP containing resuspended RBC, CTI (50 μg/mL), and fMLP was perfused over a collagen-adherent cell mixture of platelets and neutrophils, events of RBC pausing and capture to platelets and neutrophils were observed. After 25 minutes, when fibrin polymerization first became evident, a striking increase in erythrocytes firmly adherent to platelets, neutrophils, and deposited fibrin was observed. Flow was from right to left.