Evaluation of the frequency of EBV-specific T cells in the peripheral blood of patients infected with CAEBV syndrome before and after adoptive immunotherapy.

The frequency of EBV-specific cells was determined by Elispot assay on PBMCs before (■) and after (▪) CTL infusion. Bars represent the mean numbers ± SD of interferon-gamma spot-forming cells per 10⁶ PBMCs. Data from patient no. 1 were not available. ░ represents the mean ± SD of interferon-gamma spot-forming cells per 10⁶ PBMCs observed in a representative series of normal healthy donors. * indicates P = .01; ** indicatesP = .03; *** indicates P = .002.