![Fig. 2. Linkage mapping of Cdc25A on mouse chromosome 9 and comparison of the segregation of BFU-E cell-cycle status and the 2 alleles of. / Cdc25A in inbred and congenic mouse strains. (A) Genetic linkage map of the region of mouse chromosome 9 containingFv2/Stk and Cdc25A. Map distances between adjacent loci are given in cM at the left. The centromere is at the top. The linkage map was generated using a C3HheB/FeJ × C57BL/6J)F1 × C57BL/6J backcross panel of 425 animals.10 The linkage map was constructed using MAPMAKER/EXP 3.0.57 (B) Segregation of BFU-E cell-cycle status and the Cdc25A128His and Cdc25A128Gln alleles in inbred and congenic strains. Inbred and congenic strains were scored for the Cdc25A alleles by PCR. Results are presented in the left-side boxes. BFU-E cycling status of these strains has been determined by resistance to [3H]thymidine or hydroxyurea and is shown in the right-side boxes. At the top are strains shown previously to beFv2rr, and at the bottom are strains shown previously to be Fv2ss. For cell cycling status, strains marked 1 were analyzed by Suzuki and Axelrad7 and strains marked 2 were investigated in this report. B10s.C indicates B10.C-H7b(47N)/Sn; B6s.C, B6.C-H7b/By.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/100/10/10.1182_blood.v100.10.3804/4/h82223425002.jpeg?Expires=1735536473&Signature=CrCfmPAzuTKb9EzbM7Jx73~z1bJobMRiHJzLBFwVI1eAI8ZDfl~mhX~6IndmborouZmLq4HAc180VwaPFAW-gLR6ewzbVYQrP5rvRgADdMp~PTE5SlioSQo3lFCh1LEHIfxxx5Y3DkQLzJrZLAMOEBSg1GU0GCDFi1YwOl9QJx75tzVa~AgneHalGnbaAdzHSra~gW~p6~M71lpOLLWxD6XKJeU6sb~Uw8pQAxwO2WAcKtxnTK4yZ62bQo6SVOoZn8XbfYRqST5EoyoJnTJsL4wuMdA8PLj2ta-G-cSDVhN80NUEaWuUGb70TUxV6Q084Ceipiyi6yq48pfCpUmJtA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Linkage mapping of Cdc25A on mouse chromosome 9 and comparison of the segregation of BFU-E cell-cycle status and the 2 alleles of
Cdc25A in inbred and congenic mouse strains. (A) Genetic linkage map of the region of mouse chromosome 9 containingFv2/Stk and Cdc25A. Map distances between adjacent loci are given in cM at the left. The centromere is at the top. The linkage map was generated using a C3HheB/FeJ × C57BL/6J)F1 × C57BL/6J backcross panel of 425 animals.10 The linkage map was constructed using MAPMAKER/EXP 3.0.57 (B) Segregation of BFU-E cell-cycle status and the Cdc25A128His and Cdc25A128Gln alleles in inbred and congenic strains. Inbred and congenic strains were scored for the Cdc25A alleles by PCR. Results are presented in the left-side boxes. BFU-E cycling status of these strains has been determined by resistance to [3H]thymidine or hydroxyurea and is shown in the right-side boxes. At the top are strains shown previously to beFv2rr, and at the bottom are strains shown previously to be Fv2ss. For cell cycling status, strains marked 1 were analyzed by Suzuki and Axelrad7 and strains marked 2 were investigated in this report. B10s.C indicates B10.C-H7b(47N)/Sn; B6s.C, B6.C-H7b/By.
