Colony-forming cells (CFCs) and high-proliferative-potential (HPP) CFCs are maintained during ex vivo stem cell expansion.

The total number of CFCs (A) and HPP CFCs (B) were measured in long-term bone marrow cultures. Totals were compared between cultures grown in the presence (TPO) or absence (control) of TPO and uncultured (fresh) bone marrow. Reprinted from Yagi et al140 with permission.