PKC inhibition restores colony growth.

Data show erythroid colony formation from N-Ras* and control cells in the presence of vehicle or 2 μM GF109203X (conditions as in Table 1). (A) Effect on colony number. (B) Effect on colony size (average number of cells per colony). Error bars represent SD (n = 5). Significant effect of inhibitor compared with vehicle alone is indicated as follows: *P < .05, **P < .01.