Expression of CD52 by tissue dendritic cells.

Staining of adjacent sections of normal skin and small bowel (SB) with S100 and CD52 show that DCs in these tissues do not express CD52. Langerhans cells stain positively for S100 but are uniformly negative for CD52. A normal lymphoid cell in the CD52-stained skin section is shown (*). A DC in a sample of small intestinal mucosa is similarly stained with S100 but not CD52 (indicated by the arrow). Original magnification, × 400.