Fig. 5.
The Lin− c-kitLoFlk-2+ fraction of bone marrow contains B/NK-bipotential progenitors as well as committed B- and NK-cell progenitors.
Single-cell cultures were initiated as described in “Materials and methods.” Typical examples are shown of individual culture wells that were harvested 11 to 15 days later and found by flow cytometry to contain (A) B cells, (B) B cells and undifferentiated cells, (C) NK cells, and (D) both B and NK cells. The results from 3 such experiments are summarized in Table 1.