Fig. 3.
Some GPI-anchored proteins on APCs facilitate interaction with T cells.
Purified OTII-CD4+ T cells were incubated with I-Ab–expressing EL4 cells pulsed with various concentrations of OVA peptide. Data represent 1 of 2 experiments. ▨ indicates EL4 cells defective in GPI anchor biosynthesis; ▪, EL4 cells with normal GPI anchor biosynthesis; and *, difference significant (P < .05) as determined with the Studentt test.