GPI⁻ multipotential hematopoietic cells can escape CTL attack.

(A) Percentages of Ly5.1⁺ fetal liver–derived cells in various blood cells of individual mice were shown as a function of weeks after transplantation. Upper panels, control mice (n = 7) that received transplants of GPI⁺ and GPI⁻fetal liver cells, and lineage marker–negative bm12 bone marrow cells; lower panels, experimental mice (n = 9) that received transplants of fetal liver cells and lineage marker–negative bm12 bone marrow cells together with CD4⁺ T cells from bm12 mice. (B) Percentages of GPI⁻ cells in fetal liver–derived cells of various blood cell types plotted as a function of weeks after transplantation. Control and experimental mice were the same as those in panel A. (C) Percentages of GPI⁻ cells in various blood cell lineages determined 5 and 8 weeks after transplantation are shown (data for PMNCs and monocytes are at 5 weeks and for B and T cells and erythrocytes are at 8 weeks). ○ indicates control mice (n = 7); ●, experimental mice (n = 9). Bars represent mean percentages.