Fig. 8.
Influence of PKCδ inhibition on viability of B-CLL cells.
Cells (1 × 106 cells/mL) were incubated with or without Rottlerin (5 μM), which specifically inhibits PKCδ. After 24 hours apoptosis was measured by annexin/PI staining. Panel A shows the results of 12 different experiments. The proapototic effect was compared with peripheral B cells of 5 healthy donors (B).
