Figure 2.
Figure 2. A tabulated summary of major NGS studies of clonal hematopoiesis in acquired AA. Shown is a tabulated summary of major NGS studies in AA performed over the last 5 years, with annotated baseline study parameters (patients’ age, cohort size, the inclusion of patients with post-AA secondary MDS and cytogenetic abnormalities, analysis methodology, and the number of genes targeted by NGS). The overall prevalence of clonal hematopoiesis by all modalities, including WES and the rate of MDS-associated somatic mutations, are shown in the right 2 columns. Data are visually highlighted using in-table bar plots. N/A, not available; NE, not evaluable.

A tabulated summary of major NGS studies of clonal hematopoiesis in acquired AA. Shown is a tabulated summary of major NGS studies in AA performed over the last 5 years, with annotated baseline study parameters (patients’ age, cohort size, the inclusion of patients with post-AA secondary MDS and cytogenetic abnormalities, analysis methodology, and the number of genes targeted by NGS). The overall prevalence of clonal hematopoiesis by all modalities, including WES and the rate of MDS-associated somatic mutations, are shown in the right 2 columns. Data are visually highlighted using in-table bar plots. N/A, not available; NE, not evaluable.

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