Fig. 3.
Effect of compstatin on E coli–induced oxidative burst in granulocytes and monocytes in human whole blood.
T0 indicates baseline sample; T10, sample incubated for 10 minutes after addition of PBS. E coli samples (2 × 107 bacteria per milliliter) were incubated for 10 minutes after preincubation with PBS only (samples shown twice), compstatin (200 μM), or control peptide (200 μM). Data are from separate experiments with blood from 6 donors, each represented by a different symbol. The oxidative burst is given as median fluorescence intensity (MFI). Granulocytes, top panel; monocytes, bottom panel.
