Area of infarction in α2-AP^+/+ and α2-AP^−/− mice.

The areas of infarction are delineated by TTC staining of a representative heart after 12 hours of occlusion of the LAD coronary artery of α2-AP^+/+ (A) and α2-AP^−/− mice (B). Areas that appear pale white after TTC staining are infarcted. Each transverse section is cut 2 mm from the apex. Calculated infarct size is expressed as a ratio of infarct area to LV circumference. No differences were found between these 2 groups (C). Original magnification: × 8.