Fig. 4.
Effect of Bay 11-7082 on the expression of Tax and the expression and phosphorylation of p53 in HTLV-I–infected T-cell lines.
HTLV-I–infected T-cell lines were treated with 5 μM Bay 11-7082 for 48 hours and assessed by immunoblot for Tax and p53. Phosphospecific antibodies to P-Ser15 and P-Ser392 were used in the detection of phosphorylated residues of p53.