Fig. 2.
The PRV1 gene is structurally intact in patients with polycythemia vera.
gDNA was extracted from purified granulocytes isolated from 8 patients with polycythemia vera and 3 healthy controls. Ten micrograms DNA was restricted with SacI and subjected to Southern blotting. The membrane was probed with a 1.4-kb fragment of the PRV-1 cDNA. Positions of the size markers are indicated on the left.