Fig. 7.
Fig. 7. Colony morphology and colony formation of progenitors from transduced and sorted BM cells. / (A-H) Photomicrographs of small and large GM colonies produced by vector control (A-B), Rac2D57N (C-D), Rac2D57NΔCT (E-F), or Rac2D57NΔM (G-H) progenitors. Magnification × 100. (I) Quantitation of CFU derived from transduced BM cells. Values represent the mean of colony numbers in triplicate cultures. The open, hatched, and black bars denote small, medium, and large size colonies, respectively. The total number of colonies in each genotype was the sum of small, medium, and large colonies. The error bars indicate standard deviations (*P < .004 for comparisons between Rac2D57Nand any other genotype). Data shown are representative of 3 independent experiments.

Colony morphology and colony formation of progenitors from transduced and sorted BM cells.

(A-H) Photomicrographs of small and large GM colonies produced by vector control (A-B), Rac2D57N (C-D), Rac2D57NΔCT (E-F), or Rac2D57NΔM (G-H) progenitors. Magnification × 100. (I) Quantitation of CFU derived from transduced BM cells. Values represent the mean of colony numbers in triplicate cultures. The open, hatched, and black bars denote small, medium, and large size colonies, respectively. The total number of colonies in each genotype was the sum of small, medium, and large colonies. The error bars indicate standard deviations (*P < .004 for comparisons between Rac2D57Nand any other genotype). Data shown are representative of 3 independent experiments.

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