CpG-ODN therapy alters the protein expression of apoptotic-related genes in T lymphocytes.

(A) CD4⁺ and CD8⁺ T cells were purified from untreated, CpG-ODN–treated, and Neg-ODN–treated mice one day after the final ODN injection. Total detergent cell lysates were used for Western blot analysis as described in “Materials and methods.” (B) Relative intensities were normalized to the corresponding actin intensity bands.