Fig. 4.
Thymitis and cortical effacement in rhIL-7–treated BM transplant recipients.
Shown is thymic histology, day 21 after BMT, LN dose: 5 × 106 LN cells. (A) Thymic histology from a control BM transplant recipient, showing normal thymic cortex and medulla. (B) Thymus from an rhIL-7–treated BM transplant recipient with an atrophic thymus with cortical effacement. (C) Further magnification of boxed area in panel A, showing normal-appearing lymphocytes interspersed among epithelial cells of the medulla. (D) Further magnification of boxed area in panel B, showing evidence of inflammatory cells (red arrows) within the medulla. Original magnification is × 100 for panels A and B; ×1000 for C and D.
