Fig. 1.
P2X1 mediates ERK2 phosphorylation in platelets.
Western blot analyses of α,β-meATP–induced ERK2 phosphorylation in apyrase-treated washed platelets using Phospho-ERK1/2 MAP kinase (P-ERK2) and control MAP kinase (ERK2, lower panels) antibodies. (A) Time course of 2 μM α,β-meATP–induced ERK2 phosphorylation. (B) Platelets were stimulated with increasing concentrations of α,β-meATP for 2 minutes.