Fig. 7.
![Fig. 7. Allogeneic, HLA-matched MLR. / HLA.A2+ CLL cells were infected with either AAV/CD40L or AAV/EGFP and incubated for 72 hours with naive CLL cells (1:10) derived from the same patient. Then 1 × 104 CLL cells irradiated with 200 Gy were cocultured with 1 × 105 purified healthy donor T cells (HLA.A2+) for another 96 hours, pulsed with [3H]-thymidine and T-cell proliferation determined 6 hours later (cpm). The data from one representative patient are depicted. Error bars represent SEM of triplicate measurements.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/100/5/10.1182_blood.v100.5.1655.h81702001655_1655_1661/3/h81723031007.jpeg?Expires=1742856800&Signature=riOGRVa16AI3v6qN7qIRrKgBvxYE5DPx3BEoyeUxytPNoW0YqNDve3SOlik0LrWCP79ueSMx4C7FW0VOVD09eFEOq7RkcXNZIsd-CMqnXoyL8cR2QLA8zEAAiHEsWA1cxIs4GpPqem4eSbCe7JnYeEZlf23d2nqlIMgx~xGeK4lkXp-VKCczEXmk~q9gcVEuSezjsAxpkqtixezVx~lFo1YM0viVyiLrniCa0doufaPbxMWXmEcSF2b0S1l8L9Ng4JIHh8ixxipgEi3n3rH0bDxJ1J4qAm8dggG1zP2ApHZ7juPtFaMhk3WNkFVUcfL7ZTjHfBPcbSNsH3u5ghCOeA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Allogeneic, HLA-matched MLR.
HLA.A2+ CLL cells were infected with either AAV/CD40L or AAV/EGFP and incubated for 72 hours with naive CLL cells (1:10) derived from the same patient. Then 1 × 104 CLL cells irradiated with 200 Gy were cocultured with 1 × 105 purified healthy donor T cells (HLA.A2+) for another 96 hours, pulsed with [3H]-thymidine and T-cell proliferation determined 6 hours later (cpm). The data from one representative patient are depicted. Error bars represent SEM of triplicate measurements.
