Human CD34 is expressed in endothelial cells of tissues of transgenic mice.

Expression of human CD34 was detected by immunohistochemistry using a monoclonal antibody against human CD34. The left panels demonstrate lack of staining in tissues from a nontransgenic littermate as a control (original magnification, × 25). The middle panels demonstrate expression of human CD34 protein in transgenic mice at low magnification (original magnification, × 25). The right panels demonstrate expression of the protein in vascular endothelial cells at high magnification (original magnification, × 100).