Declining gelsolin levels in patients undergoing allogeneic stem cell transplantation.

The 24 patients in the study were divided into 3 groups: 10 one-year survivors, 10 early deaths (< 3 months), and 4 late deaths (3-12 months) following transplantation. Mean gelsolin levels fell precipitously during the conditioning period in all groups. For the next 5 weeks, gelsolin levels declined significantly (P = .014) only in the patients who died within 3 months after transplantation. SDs are shown only for the 1-year survivors and patients experiencing early deaths.