Prothrombinase-supporting activity of patient and normal isolated VLDL.

Rates of thrombin formation were determined at numerous concentrations of isolated normal VLDL (○) and VLDL from 3 patients with biphasic transmittance waveform. VLDL concentrations were measured as triglycerides. A qualitative difference in potency (prothrombinase activity/VLDL) is observed in these data in that the respective patient specimens were 3.3 (▴), 4.1 (●), and 7.8 (▪) times more potent than normal VLDL (○).