American Society of Hematology

Fig. 4.

$Fig. 4. Effect of specific antagonists of IL-1R on E-selectin expression. / Anti–TNF-α (A) or anti–IL-1RI (B) blocking antibodies or IL-1ra (C) were used in cultures of HUVECs activated by polyclonal anti–β2-GPI (200 μg/mL) or NHS IgG fractions (200 μg/mL) or by TNF-α (1 ng/mL), IL-1β (1 U/mL), or LPS (10 ng/mL). Data are expressed as OD values, mean ± SD of 3 different experiments. *P < .05 versus medium.$

Effect of specific antagonists of IL-1R on E-selectin expression.

Anti–TNF-α (A) or anti–IL-1RI (B) blocking antibodies or IL-1ra (C) were used in cultures of HUVECs activated by polyclonal anti–β₂-GPI (200 μg/mL) or NHS IgG fractions (200 μg/mL) or by TNF-α (1 ng/mL), IL-1β (1 U/mL), or LPS (10 ng/mL). Data are expressed as OD values, mean ± SD of 3 different experiments. *P < .05 versus medium.

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