Gene-expression profiles obtained from desferrioxamine-treated HeLa cells and HFE-expressing HeLa cells.

(A) Total RNA derived from HeLa cells treated with 100 μM desferrioxamine (D) for 8 hours or total RNA derived from HeLa cells that express HFE from an inducible transgene was analyzed on the IronChip in comparison with control samples. The average ratios of differentially expressed genes and their standard deviations are shown. (B) Comparison of the gene-expression profiles from desferrioxamine-treated and HFE-expressing HeLa cells. Genes with increased expression in desferrioxamine-treated and/or HFE-expressing cells are shown in positive numbers and those with decreased expression in negative numbers.