Fig. 2.
Fig. 2. Monoclonal antibodies can inhibit immune thrombocytopenia in normal mice induced by either anti-αIIb or anti-β3 antibody. / The indicated dose of monoclonal antibody anti–TER-119 or 50 mg IVIG (■) was administered to BALB/c mice followed by (A) anti-αIIb or (B) anti-β3 antibody at 24 hours. After a further 24 hours, platelet counts were performed. Normal, ITP, x-axis and y-axis are as described in Figure 1; n = 7 for each data point. *P < .05; ***P < .001 as compared with ITP mice. Error bars indicate SEM.

Monoclonal antibodies can inhibit immune thrombocytopenia in normal mice induced by either anti-αIIb or anti-β3 antibody.

The indicated dose of monoclonal antibody anti–TER-119 or 50 mg IVIG (■) was administered to BALB/c mice followed by (A) anti-αIIb or (B) anti-β3 antibody at 24 hours. After a further 24 hours, platelet counts were performed. Normal, ITP, x-axis and y-axis are as described in Figure 1; n = 7 for each data point. *P < .05; ***P < .001 as compared with ITP mice. Error bars indicate SEM.

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